X-Clarity
The X-CLARITY™ Tissue Clearing System II from Logos Biosystems is an advanced electrophoretic tissue clearing platform, designed to accelerate high-resolution 3D imaging and deep-tissue analysis. Utilizing the CLARITY method, this system embeds biological samples in a hydrogel matrix, preserving cellular and subcellular structures while rendering tissues optically transparent for light-sheet microscopy, confocal imaging, and molecular phenotyping.
With a high-efficiency lipid extraction process, the X-CLARITY system clears a whole mouse brain in just 6 hours—eight times faster than conventional passive clearing methods. Its SDS-based clearing buffer is optimized for uniform tissue processing, minimizing sample degradation and ensuring consistent fluorescence preservation for downstream applications.
This system facilitates neuroscience research, connectomics, and structural-functional mapping, making it an essential tool for single-cell analysis, immunolabeling, and volumetric imaging across various biological fields.
Core Research Facilities | Site
Ein Karem
Bio Medicine Research Core Facility
Contacts
- Dr. Miriam Kott-Gutkowski
- 02-6757565
- miriamk@ekmd.huji.ac.il